Derek and the Dominos were a blues-rock band formed in the spring of 1970 by guitarist and singer Eric Clapton with keyboardist Bobby Whitlock, bassist Carl Radle and drummer Jim Gordon, who had all played with Clapton in Delaney, Bonnie & Friends.
The band released only one studio album, Layla and Other Assorted Love Songs, which featured prominent contributions from guest guitarist Duane Allman from the Allman Brothers Band. The album went on to receive critical acclaim, but initially faltered in sales and in radio airplay. Although released in 1970 it was not until March 1972 that the album’s single “Layla” (a tale of unrequited love inspired by Clapton’s relationship with his friend George Harrison’s wife, Pattie Boyd Harrison) would make the top ten in both the United States and the United Kingdom. The album, which has received praise from both critics and fans alike, is often considered to be the defining achievement of Clapton’s career.
Source: http://en.wikipedia.org/wiki/Derek_and_the_Dominos